NFL Week 2 Best Game to Bet: Los Angeles Chargers vs. Kansas City Chiefs

The best NFL game from Week 2 could well be the first one of the week, as the Chargers will travel to Kansas City on Thursday for a battle of Super Bowl contenders from the AFC West. Kickoff is scheduled for 8:20 p.m. EDT from Arrowhead Stadium, and you can watch this game on Amazon Prime.

Coming off a dominant 44-21 victory in Arizona, the Chiefs open as 3.5-point favorites at home, but the Chargers are riding high as well after a 24-19 home win over the Raiders. Plenty of scoring is expected from these high-powered offenses, as the over/under of 54 points is the highest among Week 2 games on Kansas sportsbooks. These lines could shift throughout the week as betting action comes in and we gain clarification on notable injuries, including the hamstring injury that receiver Keenan Allen suffered in Los Angeles’ season opener. Star Chiefs quarterback Patrick Mahomes banged up the wrist on his non-throwing hand, but he played through the injury against the Cardinals and didn’t appear to be hampered in any way.

There are plenty of NFL betting sites available across the United States, and most operate in several states where sports betting is legal. Kansas recently launched KS betting apps, and many Missouri residents will head over the border to bet on sportsbooks like BetMGM Kansas and Caesars KS. In addition, you can use DraftKings Sportsbook in any of the online betting states, and the variety available on DraftKings’ Same Game Parlay feature makes it an ideal operator on which to bet on this potentially high-scoring game.

Same Game Parlay bets allow you to combine multiple bets on one game into a single parlay. The legs of your Same Game Parlay can consist of wagers on the moneyline (Chiefs -170), spread or point total for the entire game, as well as prop bets regarding segments of the game and individual player performances. You can also place individual bets on all of these options, but using the Same Game Parlay feature on DraftKings Sportsbook KS will grant you access to a greater variety of prop bets. For instance, the spread is set at Chiefs -3.5 points, but betting with the Same Game Parlay feature unlocks alternate spreads on the Chiefs ranging from +6.5 points to -13.5 points at one-point intervals.


Sasha has been writing about sports since 2014. He's a huge New York sports fan who has written columns for RotoWire, Yahoo Sports and CBS Sports.